Acetaminophen (Paracetamol)

Acetaminophen also as Paracetamol, is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever.

Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body.

How should this medicine be used?

Acetaminophen comes as a tablet, capsule, suspension or solution (liquid), extended-release (long-acting) tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth), to take by mouth, with or without food.

Acetaminophen is available without a prescription, but your doctor may prescribe acetaminophen to treat certain conditions. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

If you are giving acetaminophen to your child, read the package label carefully to make sure that it is the right product for the age of the child. Do not give children acetaminophen products that are made for adults. Some products for adults and older children may contain too much acetaminophen for a younger child.

Check the package label to find out how much medication the child needs. If you know how much your child weighs, give the dose that matches that weight on the chart. If you don’t know your child’s weight, give the dose that matches your child’s age. Ask your child’s doctor if you don’t know how much medication to give your child.

Acetaminophen comes in combination with other medications to treat cough and cold symptoms. Ask your doctor or pharmacist for advice on which product is best for your symptoms.

Check nonprescription cough and cold product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose.

This is especially important if you will be giving cough and cold medications to a child. Swallow the extended-release tablets whole; do not split, chew, crush, or dissolve them.

Place the orally disintegrating tablet (‘Meltaways’) in your mouth and allow to dissolve or chew it before swallowing.

Shake the suspension well before each use to mix the medication evenly. Always use the measuring cup or syringe provided by the manufacturer to measure each dose of the solution or suspension.

Do not switch dosing devices between different products; always use the device that comes in the product packaging.

Stop taking acetaminophen and call your doctor if your symptoms get worse, you develop new or unexpected symptoms, including redness or swelling, your pain lasts for more than 10 days, or your fever gets worse or lasts more than 3 days.

Also stop giving acetaminophen to your child and call your child’s doctor if your child develops new symptoms, including redness or swelling, or your child’s pain lasts for longer than 5 days, or fever get worse or lasts longer than 3 days.

Do not give acetaminophen to a child who has a sore throat that is severe or does not go away, or that occurs along with fever, headache, rash, nausea, or vomiting. Call the child’s doctor right away, because these symptoms may be signs of a more serious condition.

Other uses for this medicine
Acetaminophen may also be used in combination with aspirin and caffeine to relieve the pain associated with migraine headache.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking acetaminophen,
Tell your doctor and pharmacist if you are allergic to acetaminophen, any other medications, or any of the ingredients in the product. Ask your pharmacist or check the label on the package for a list of ingredients.

Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take. Be sure to mention anticoagulants (‘blood thinners’) such as warfarin (Coumadin); isoniazid (INH); certain medications for seizures including carbamazepine (Tegretol), phenobarbital, and phenytoin (Dilantin); medications for pain, fever, coughs, and colds; and phenothiazines (medications for mental illness and nausea).

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Tell your doctor if you have ever developed a rash after taking acetaminophen.

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking acetaminophen, call your doctor.

If you drink three or more alcoholic beverages every day, do not take acetaminophen. Ask your doctor or pharmacist about the safe use of alcoholic beverages while taking acetaminophen.

You should know that combination acetaminophen products for cough and colds that contain nasal decongestants, antihistamines, cough suppressants, and expectorants should not be used in children younger than 2 years of age. Use of these medications in young children can cause serious and life-threatening effects or death.

In children 2 through 11 years of age, combination cough and cold products should be used carefully and only according to the directions on the label.

If you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that some brands of acetaminophen chewable tablets may be sweetened with aspartame. a source of phenylalanine.

What should I do if I forget a dose?

This medication is usually taken as needed. If your doctor has told you to take acetaminophen regularly, take the missed dose as soon as you remember it.

However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this Acetaminophen cause?

Acetaminophen may cause side effects.
Some side effects can be serious. If you experience any of the following symptoms, stop taking acetaminophen and call your doctor immediately or get emergency medical attention:
red, peeling or blistering skin
rash
hives
itching
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
hoarseness
difficulty breathing or swallowing

Acetaminophen may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

If someone takes more than the recommended dose of acetaminophen, get medical help immediately, even if the person does not have any symptoms.

Symptoms of overdose may include the following:
nausea
vomiting
loss of appetite
sweating
extreme tiredness
unusual bleeding or bruising
pain in the upper right part of the stomach
yellowing of the skin or eyes
flu-like symptoms

Hydrochlorothiazide

Why is this medication prescribed?

HCTZ is used alone or in combination with other medications to treat high blood pressure. Hydrochlorothiazide is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids.

Hydrochlorothiazide is in a class of medications called diuretics (‘water pills’). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure.

These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

How should this medicine be used?

Hydrochlorothiazide as 12.5mg, 25mg, or 50mg comes as a tablet, capsule, and solution (liquid) to take by mouth. It usually is taken once or twice a day. When used to treat edema, hydrochlorothiazide may be taken daily or only on certain days of the week. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Hydrochlorothiazide controls high blood pressure but does not cure it.

Continue to take hydrochlorothiazide even if you feel well. Do not stop taking hydrochlorothiazide without talking to your doctor.
Other uses for this medicine
Hydrochlorothiazide may also be used to treat patients with diabetes insipidus and to prevent kidney stones in patients with high levels of calcium in their blood. Talk to your doctor about the possible risks of using this medicine for your condition.

This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking hydrochlorothiazide,
tell your doctor and pharmacist :

If you are allergic to hydrochlorothiazide, ‘sulfa drugs’, penicillin, or any other drugs.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: barbiturates such as phenobarbital and secobarbital (Seconal); corticosteroids such as betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, others), fludrocortisone (Florinef), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, others), prednisolone (Prelone, others), prednisone (Deltasone, Meticorten, Sterapred, others), and triamcinolone (Aristocort, Azmacort); corticotropin (ACTH, H.P., Acthar Gel); insulin and oral medications for diabetes; lithium (Eskalith, Lithobid); medications for high blood pressure or pain; nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others).

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

If you are taking cholestyramine or colestipol, take them 1 hour before or 4 hours after taking hydrochlorothiazide.

Tell your doctor if you have kidney disease. Your doctor may tell you not to take hydrochlorothiazide.

Tell your doctor if you have or have ever had diabetes, asthma, gout, systemic lupus erythematosus (SLE, a chronic inflammatory condition), high cholesterol, or kidney or liver disease.

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking hydrochlorothiazide, call your doctor immediately.

Plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Hydrochlorothiazide may make your skin sensitive to sunlight and increase your risk of a certain types of skin cancer. Your doctor will check your skin for skin cancers during your treatment with hydrochlorothiazide. Call your doctor if you notice any new skin changes or growths.
you should know that hydrochlorothiazide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking hydrochlorothiazide.

To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Alcohol can add to these side effects.

What special dietary instructions should I follow?

If your doctor prescribes a low-salt or low-sodium diet, or to eat or drink increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet, follow these instructions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule.

Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Tell your doctor if any of these symptoms are severe or do not go away:
frequent urination
diarrhea
loss of appetite
headache
hair loss
If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:
dry mouth; thirst; nausea; vomiting; weakness, tiredness; drowsiness; restlessness; confusion; muscle weakness, pain, or cramps; fast heartbeat and other signs of dehydration and electrolyte imbalance
blisters or peeling skin
hives
rash
itching
difficulty breathing or swallowing
unusual bleeding or bruising
ongoing pain that begins in the stomach area, but may spread to the back
joint pain or swelling
changes in vision, eye pain, or swelling or redness in or around the eye

Hydrocortisone Injection

It is used to treat symptoms of low corticosteroid levels (lack of certain substances that are usually produced by the body and are needed for normal body functioning). It is also used to treat severe allergic reactions. Hydrocortisone injection is used in the management of multiple sclerosis (a disease in which the nerves do not function properly), lupus (a disease in which the body attacks many of its own organs), gastrointestinal disease, and certain types of arthritis.

Hydrocortisone injection is also used to treat certain conditions that affect the blood, skin, eyes, nervous system, thyroid, kidneys, and lungs. Hydrocortisone injection is in a class of medications called corticosteroids. It works to treat people with low levels of corticosteroids by replacing steroids that are normally produced naturally by the body. It also works to treat other conditions by reducing swelling and redness and by changing the way the immune system works.

How should this medicine be used?

Hydrocortisone injection comes as powder to be mixed with liquid to be injected intramuscularly (into a muscle) or intravenously (into a vein). Your dosing schedule will depend on your condition and on how you respond to treatment.

You may receive hydrocortisone injection in a hospital or medical facility, or you may be given the medication to use at home. If you will be using hydrocortisone injection at home, your healthcare provider will show you how to inject the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems using hydrocortisone injection.

Your doctor may change your dose of hydrocortisone injection during your treatment to be sure that you are always using the lowest dose that works for you. Your doctor may also need to change your dose if you experience unusual stress on your body such as surgery, illness, or infection.

Tell your doctor if your symptoms improve or get worse or if you get sick or have any changes in your health during your treatment.

What special precautions should I follow?

Before receiving hydrocortisone injection,

Tell your doctor and pharmacist if you are allergic to hydrocortisone, any other medications, benzyl alcohol, or any of the ingredients in hydrocortisone injection. Ask your pharmacist for a list of the ingredients.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: aminoglutethimide (Cytadren; no longer available in U.S.); amphotericin B (Abelcet, Ambisome, Amphotec); anticoagulants (‘blood thinners’) such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn) and selective COX-2 inhibitors such as celecoxib (Celebrex); carbamazepine (Equetro, Tegretol, Teril); cholinesterase inhibitors such as donepezil (Aricept, in Namzaric), galantamine (Razadyne), neostigmine (Bloxiverz), pyridostigmine (Mestinon, Regonol), and rivastigmine (Exelon); cholestyramine (Prevalite); cyclosporine (Gengraf, Neoral, Sandimmune); medications for diabetes including insulin; digoxin (Lanoxin); diuretics (‘water pills’); erythromycin (E.E.S., Ery-Tab, Erythrocin, others); estrogens including hormonal contraceptives (birth control pills, patches, rings, implants, and injections); isoniazid (Laniazid, Rifamate, in Rifater); ketoconazole (Nizoral, Xolegel); phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Tell your doctor if you have a fungal infection (other than on your skin or nails). Your doctor will probably tell you not to use hydrocortisone injection. Also, tell your doctor if you have idiopathic thrombocytopenic purpura (ITP; an ongoing condition that may cause easy bruising or bleeding due to an abnormally low number of platelets in the blood). Your doctor probably will not give you hydrocortisone intramuscularly, if you have ITP.

Tell your doctor if you have or have ever had tuberculosis (TB: a type of lung infection); cataracts (clouding of the lens of the eye); glaucoma (an eye disease); Cushing’s syndrome (condition where the body produces too much of the hormone cortisol); diabetes; high blood pressure; heart failure; a recent heart attack; emotional problems, depression or other types of mental illness; myasthenia gravis (a condition in which the muscles become weak); osteoporosis (condition in which the bones become weak and fragile and can break easily); seizures; ulcers; or liver, kidney, heart, intestinal, or thyroid disease. Also tell your doctor if you have any type of untreated bacterial, parasitic, or viral infection anywhere in your body or a herpes eye infection (a type of infection that causes a sore on the eyelid or eye surface).

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving hydrocortisone injection, call your doctor.

If you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving hydrocortisone injection. do not have any vaccinations (shots to prevent diseases) without talking to your doctor. You should know that hydrocortisone injection may decrease your ability to fight infection and may prevent you from developing symptoms if you get an infection.

Stay away from people who are sick and wash your hands often while you are using this medication. Be sure to avoid people who have chicken pox or measles. Call your doctor immediately if you think you may have been around someone who had chicken pox or measles..

What side effects can this medication cause?

Hydrocortisone injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Headache
Dizziness
Slowed healing of cuts and bruises
Acne
Thin, fragile, or dry skin
Red or purple blotches or lines under the skin
Skin depressions at the injection site
Increased body fat or movement to different areas of your body
Difficulty falling asleep or staying asleep
Inappropriate happiness
Extreme changes in mood changes in personality
Extreme tiredness
Depression
increased sweating
muscle weakness
joint pain
dizziness
irregular or absent menstrual periods
increased appetite
hiccups

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

sore throat, fever, chills, cough, or other signs of infection
seizures
vision problems
swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
swelling or pain in the stomach
difficulty breathing or swallowing
shortness of breath
sudden weight gain
rash
hives
itching
abnormal skin patches in the mouth, nose, or throat

Hydrocortisone injection may cause children to grow more slowly. Your child’s doctor will watch your child’s growth carefully while your child is using hydrocortisone injection.

Talk to your child’s doctor about the risks of giving this medication to your child.
People who use hydrocortisone injection for a long time may develop glaucoma or cataracts.

Talk to your doctor about the risks of using hydrocortisone injection and how often you should have your eyes examined during your treatment.

Hydrocortisone injection may increase your risk of developing osteoporosis. Talk to your doctor about the risks of using this medication.

Hydrocortisone injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication..

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