Doxycycline

Doxycycline as 100mg is an antibiotic used to treat a variety of infections caused by bacteria.

Doxycycline is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air and to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack).

It is also used to prevent malaria. Doxycycline is also used along with other medications to treat acne and rosacea (a skin disease that causes redness, flushing, and pimples on the face). Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea. Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria.

It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne. It works to treat rosacea by decreasing the inflammation that causes this condition.

Antibiotics such as doxycycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should Doxycycline be used?

Doxycycline comes as a capsule, tablet, delayed-release tablet, and suspension (liquid) to take by mouth. Doxycycline is usually taken once or twice a day. Drink a full glass of water with each dose.

If your stomach becomes upset when you take doxycycline, you may take it with food or milk. Talk with your doctor or pharmacist about the best way to take doxycycline. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take doxycycline exactly as directed.

Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the delayed-release tablets whole; do not split, chew, or crush them.

If you cannot swallow certain delayed-release tablets (Doryx; generics) whole, carefully break up the tablet and sprinkle the contents of the tablet on a spoonful of cold or room temperature (not hot) applesauce. Be careful not to crush or damage any of the pellets while you are breaking up the tablet. Eat the mixture right away and swallow without chewing. If the mixture cannot be eaten right away it should be discarded.

Shake the suspension well before each use to mix the medication evenly.
If you are taking doxycycline for the prevention of malaria, start taking it 1 or 2 days before traveling to an area where there is malaria. Continue taking doxycycline each day you are in the area, and for 4 weeks after leaving the area. You should not take doxycycline for the prevention of malaria for more than 4 months.

Continue to take doxycycline even if you feel well. Take all the medication until you are finished, unless your doctor tells you otherwise.

One doxycycline product may not be able to be substituted for another. Be sure that you receive only the type of doxycycline that was prescribed by your doctor. Ask your pharmacist if you have any questions about the type of doxycycline you were given.
Other uses for this medicine
Doxycycline may also be used for the treatment of malaria. It may also be used to treat Lyme disease or to prevent Lyme disease in certain people who have been bitten by a tick. It may also be used to prevent infection in people who were sexually attacked. Talk to your doctor about the possible risks of using this medication for your condition.

What special precautions should I follow?

Before taking doxycycline,
tell your doctor and pharmacist if

You are allergic to doxycycline, minocycline (Dynacin, Minocin, Solodyn, Ximino), tetracycline (Achromycin V, in Pylera), demeclocycline, any other medications, sulfites, or any of the ingredients in doxycycline capsules, tablets, extended-release tablets, or suspension. Ask your pharmacist for a list of the ingredients.

Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: acitretin; anticoagulants (‘blood thinners’) such as warfarin (Jantoven); bismuth subsalicylate; carbamazepine (Epitol, Tegretol, others); isotretinoin (Absorica, Clavaris, Myorisan, Zenatane); penicillin; phenobarbital; phenytoin (Phenytek); and proton pump inhibitors such as dexlansoprazole (Dexilant), esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid, in Talicia), pantoprazole (Protonix), and rabeprazole (Aciphex).

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, iron products, and laxatives containing magnesium interfere with doxycycline, making it less effective.

Take doxycycline 1–2 hours before or 1–2 hours after taking antacids, calcium supplements, and laxatives containing magnesium. Take doxycycline 2 hours before or 3 hours after iron preparations and vitamin products that contain iron.

Tell your doctor if you have or have ever had lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), intracranial hypertension (pseudotumor cerebri; high pressure in the skull that may cause headaches, blurry or double vision, vision loss, and other symptoms), a yeast infection in your mouth or vagina, surgery on your stomach, asthma, or kidney or liver disease.

Also, tell you doctor if you have diarrhea.

You should know that doxycycline may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.

Tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking doxycycline, call your doctor immediately. Doxycycline can harm the fetus.

Tell your doctor if you are breastfeeding. Your doctor may tell you not to breastfeed during your treatment with doxycycline.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen.

Doxycycline may make your skin sensitive to sunlight. Tell your doctor right away if you get a sunburn.

You should know that when you are receiving doxycycline for prevention of malaria, you should also use protective measures such as effective insect repellent, mosquito nets, clothing covering the whole body, and staying in well-screened areas, especially from early nighttime until dawn. Taking doxycycline does not give you full protection against malaria.

You should know that when doxycycline is used during pregnancy or in babies or children up to 8 years of age, it can cause the teeth to become permanently stained and can cause problems with bone growth. Doxycycline should not be used in children under 8 years of age except for inhalational anthrax, Rocky Mountain spotted fever, or if your doctor decides it is needed.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Doxycycline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
nausea
vomiting
diarrhea
loss of appetite
itching of the rectum
swelling, redness, burning, itching, or irritation of the vagina
vaginal discharge
painful or difficult urination
sore throat or nose
swollen tongue
dry mouth
anxiety
back pain
changes in color of skin, scars, nails, eyes, or mouth
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
headache
blurred vision, seeing double, or loss of vision
rash that may occur with fever or swollen glands
hives
skin redness, peeling or blistering
difficulty breathing or swallowing
swelling of the eyes, face, throat, tongue, or lips
unusual bleeding or bruising
watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment
a return of fever, sore throat, chills, or other signs of infection
joint pain
discoloration of permanent (adult) teeth

Doxycycline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What other information should I know?

Keep all appointments with your doctor and laboratory. Your doctor will want to check your response to doxycycline.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking doxycycline.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the doxycycline, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Tetracycline

Tetracycline as capsule, ointment or injection is an antibiotic used to treat infections caused by bacteria including pneumonia and other respiratory tract infections; ; certain infections of skin, eye, lymphatic, intestinal, genital and urinary systems; and certain other infections that are spread by ticks, lice, mites, and infected animals.

It is also used along with other medications to treat acne. Tetracycline is also used to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack).

It can also be used in patients who cannot be treated with penicillin to treat certain types of food poisoning, and anthrax (a serious infection that may be spread on purpose as part of a bioterror attack).

Tetracycline is in a class of medications called tetracycline antibiotics. It works by preventing the growth and spread of bacteria.

Antibiotics such as tetracycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should Tetracycline be used?

Tetracycline comes as a capsule to take by mouth or as an ointment cream. It is usually taken two or four times daily.

Tetracycline should be taken on an empty stomach, at least 1 hour before or 2 hours after meals or snacks. Drink a full glass of water with each dose of tetracycline. Do not take tetracycline with food, especially dairy products such as milk, yogurt, cheese, and ice cream.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tetracycline exactly as directed.

Do not take more or less of it or take it more often than prescribed by your doctor.
Other uses for this medicine
Tetracycline is also sometimes used to treat Lyme disease and malaria, and to prevent plague and tularemia in people who have been exposed to plague or tularemia germs.

Talk to your doctor about the risks of using this medication for your condition.

What special precautions should I follow?

Before taking tetracycline,
tell your doctor and pharmacist if:

You are allergic to tetracycline, minocycline, doxycycline, demeclocycline, any other medications, or any of the ingredients in the tetracycline capsule.

Tell your doctor and pharmacist what prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants (‘blood thinners’) such as warfarin (Coumadin, Jantoven), and penicillin.

Be aware that antacids containing magnesium, aluminum, calcium, or sodium bicarbonate, calcium supplements, zinc products, iron products, and laxatives containing magnesium interfere with tetracycline, making it less effective.

Take tetracycline 2 hours before or 6 hours after antacids, calcium supplements, zinc products, and laxatives containing magnesium. Take tetracycline 2 hours before or 4 hours after iron preparations and vitamin products that contain iron. Take tetracycline 2 hours before or after zinc containing products.

Tell your doctor if you have or have ever had lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), or kidney disease.

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking tetracycline, call your doctor immediately. Tetracycline can harm the fetus.

Tetracycline may make your skin sensitive to sunlight. Tell your doctor right away if you get a sunburn.

You should know that when tetracycline is used during pregnancy or in babies or children up to age 8, it can cause the teeth to become permanently stained. Tetracycline should not be used in children under age 8 unless your doctor decides it is needed.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Tetracycline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
nausea
vomiting
diarrhea
itching of the rectum or vagina
swollen tongue
black or hairy tongue
sore or irritated throat
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
headache
blurred vision, seeing double, or loss of vision
skin rash
hives
swelling of the face, throat, tongue, lips, and eyes
difficulty breathing or swallowing
joint stiffness or swelling
unusual bleeding or bruising
chest pain
a return of fever, sore throat, chills, or other signs of infection
watery or bloody stools , stomach cramps, or fever during treatment or for up to two or more months after stopping treatment

Tetracycline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to tetracycline.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking tetracycline.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the tetracycline, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you

Medroxyprogesterone [Depo]

Medroxyprogesterone as common brand name Depo Provera is an intramuscular and subcutaneous injection used to as a contraceptive to prevent pregnancy.

Medroxyprogesterone subcutaneous injection is also used to treat endometriosis- (a condition in which the type of tissue that lines the uterus (womb) grows in other areas of the body and causes pain, heavy or irregular menstruation [periods], and other symptoms).

Medroxyprogesterone is in a class of medications called progestins. It works to prevent pregnancy by preventing ovulation (the release of eggs from the ovaries). Medroxyprogesterone also thins the lining of the uterus. This helps to prevent pregnancy in all women and slows the spread of tissue from the uterus to other parts of the body in women who have endometriosis.

Depo injection is a very effective method of birth control but does not prevent the spread of human immunodeficiency virus (HIV, the virus that causes acquired immunodeficiency syndrome [AIDS]) or other sexually transmitted diseases.

WARNING

Medroxyprogesterone injection may decrease the amount of calcium stored in your bones. The amount of calcium in your bones may not return to normal even after you stop using the injection and this may cause osteoporosis even after menopause.

How should this medicine be used?

Medroxyprogesterone intramuscular injection comes as a suspension (liquid) to be injected into the buttocks or upper arm. It is usually given once every 3 months (13 weeks) by a healthcare provider in an office or clinic.

Medroxyprogesterone subcutaneous injection comes as suspension to be injected just under the skin. It is usually injected once every 12 to 14 weeks by a healthcare provider in an office or clinic.

You must receive your first medroxyprogesterone subcutaneous or intramuscular injection only at a time when there is no possibility that you are pregnant. Therefore, you may only receive your first injection during the first 5 days of a normal menstrual period, during the first 5 days after you give birth if you are not planning to breast-feed your baby, or during the sixth week after giving birth if you are planning to breast-feed your baby.

If you have been using a different method of birth control and are switching to this injection, your doctor will tell you when you should receive your first injection.

What special precautions should I follow?

Before using medroxyprogesterone injection,
tell your doctor and pharmacist if:

You are allergic to medroxyprogesterone (Depo-Provera, depo-subQ provera 104, Provera, in Prempro, in Premphase) or any other medications.

Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Tell your doctor if you or anyone in your family has or has ever had breast cancer or diabetes.

Also tell your doctor if you have or have ever had problems with your breasts such as lumps, bleeding from your nipples, an abnormal mammogram (breast x-ray), or fibrocystic breast disease (swollen, tender breasts and/or breast lumps that are not cancer); unexplained vaginal bleeding;irregular or very light menstrual periods; excessive weight gain or fluid retention before your period; blood clots in your legs, lungs, brain, or eyes; stroke or mini-stroke; migraine headaches; seizures; depression; high blood pressure; heart attack; asthma; or heart, liver, or kidney disease.

Tell your doctor if you think you might be pregnant, you are pregnant, or you plan to become pregnant. If you become pregnant while using medroxyprogesterone injection, call your doctor immediately. Medroxyprogesterone may harm the fetus.

Tell your doctor if you are breast-feeding. You may use medroxyprogesterone injection while you are breast-feeding as long as your baby is 6 weeks old when you receive your first injection. Some medroxyprogesterone may be passed to your baby in your breast milk but this has not been shown to be harmful. Studies of babies who were breast-fed while their mothers were using medroxyprogesterone injection showed that the babies were not harmed by the medication.

Tell your doctor if you or anyone in your family has osteoporosis; if you have or have ever had any other bone disease or anorexia nervosa (an eating disorder); or if you drink a lot of alcohol or smoke a great deal.

Tell your doctor if you take any of the following medications: corticosteroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); or medications for seizures such as carbamazepine (Tegretol), phenytoin (Dilantin), or phenobarbital (Luminal, Solfoton).

If you are having surgery, including dental surgery, tell the doctor or dentist that you are using medroxyprogesterone injection.

You should know that your menstrual cycle will probably change while you are using medroxyprogesterone injection. At first, your periods will probably be irregular, and you may experience spotting between periods. If you continue to use this medication, your periods may stop completely. Your menstrual cycle will probably return to normal some time after you stop using this medication.

What special dietary instructions should I follow?

You should eat plenty of foods that are rich in calcium and vitamin D while you are receiving medroxyprogesterone injection to help decrease the loss of calcium from your bones.

Your doctor will tell you which foods are good sources of these nutrients and how many servings you need each day. Your doctor also may prescribe or recommend calcium or vitamin D supplements.

What should I do if I forget a dose?

If you miss an appointment to receive an injection of medroxyprogesterone, call your doctor. You may not be protected from pregnancy if you do not receive your injections on schedule. If you do not receive an injection on schedule, your doctor will tell you when you should receive the missed injection.

Your doctor will probably administer a pregnancy test to be sure that you are not pregnant before giving you the missed injection. You should use a different method of birth control, such as condoms until you receive the injection that you missed.

What side effects can this Medroxyprogesterone cause?

Medroxyprogesterone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
changes in menstrual periods
weight gain
weakness
tiredness
nervousness
irritability
depression
difficulty falling asleep or staying asleep
hot flashes
breast pain, swelling, or tenderness
stomach cramps or bloating
leg cramps
back or joint pain
acne
loss of hair on scalp
swelling, redness, irritation, burning, or itching of the vagina
white vaginal discharge
changes in sexual desire
cold or flu symptoms
pain, irritation, lumps, redness or scarring in the place where the medication was injected
Some side effects can be serious.

The following side effects are uncommon, but if you experience any of them, call your doctor immediately:
sudden shortness of breath
sudden sharp or crushing chest pain
coughing up blood
severe headache
nausea
vomiting
dizziness or faintness
change or loss of vision
double vision
bulging eyes
difficulty speaking
weakness or numbness in arm
seizure
yellowing of the skin or eyes
extreme tiredness
pain, swelling, warmth, redness, or tenderness in one leg only
menstrual bleeding that is heavier or lasts longer than normal
severe pain or tenderness just below the waist
rash
hives
itching
difficulty breathing or swallowing
swelling of the hands, feet, ankles, or lower legs
difficult, painful, or frequent urination
constant pain, pus, warmth, swelling, or bleeding in the place where the medication was injected

If you are younger than 35 years old and began to receive medroxyprogesterone injection in the last 4 to 5 years, you may have a slightly increased risk that you will develop breast cancer.

Medroxyprogesterone injection may also increase the chance that you will develop a blood clot that moves to your lungs or brain.

Talk to your doctor about the risks of using this medication.
Medroxyprogesterone injection is a long-acting birth control method. You might not become pregnant for some time after you receive your last injection.

Talk to your doctor about the effects of using this medication if you plan to become pregnant in the near future.

Medroxyprogesterone injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

WARNINGS
Medroxyprogesterone injection may decrease the amount of calcium stored in your bones. The longer you use this medication, the more the amount of calcium in your bones may decrease. The amount of calcium in your bones may not return to normal even after you stop using medroxyprogesterone injection.

Loss of calcium from your bones may cause osteoporosis (a condition in which the bones become thin and weak) and may increase the risk that your bones might break at some time in your life, especially after menopause (change of life).

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